| Autoantibodies against the antigens SS‑A and SS‑B are found in most patients suffering from primary Sjögren's syndrome. Inflammatory processes of the salivary and lachrymal glands are characteristic for this
disorder. Also SLE patients with sicca syndrome exhibit antibodies against SS‑A and SS‑B. More importantly, anti-SS‑A antibodies are present in > 80% of mothers
of infants with congenital heart block. The risk of an
anti‑SS‑A positive mother giving birth to an infant suffering from neonatal lupus syndrome is about 5 - 10%. An isolated anti‑SS‑B finding is very rare.
SS‑B antibodies mostly appear together with SS‑A antibodies in a patient serum. |
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| Tests |
12 x 8 Tests |
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| Calculation |
quantitative |
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| Range |
0 – 200 U/ml |
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| Cut-off |
25 U/ml |
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| Sensitivity |
1 U/ml |
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| Calibration |
CDC |
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| Substrate |
TMB / 450 nm |
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Instruction for Use: ORG 508-0508-01-gb.pdf
Material-Safety-Datasheet: ORG 508.pdf