| Autoantibodies directive against the anionic phospholipid
Cardiolipin are primarily found in patients suffering
from primary and secondary antiphospholipid
syndrome. Those patients manifest clinical manifestations
like thrombosis of veins and arteries, thrombocytopenia
and recurrent fetal loss. Anti-Cardiolipin autoantibodies
are found in the immunoglobulin classes
IgG, IgM and/or IgA. The Anti-Cardiolipin screen assay
permits a semiquantitative screening of autoantibodies
against Cardiolipin. Further differentiation and
typing should be carried out by using the individual
test kits. All test are additionally coated with human
β2-Glycoprotein I. |
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| Tests |
ORG 515/515A/S: 12 x 8 Tests
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| Calculation |
Screen: semi-quantitative
IgG/IgM/IgA: quantitative |
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| Range |
Screen: 0 – 90 U/ml
IgG: 0 – 120 GPL U/ml
IgM: 0 – 80 MPL U/ml
IgA: 0 – 120 APL U/ml |
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| Cut-off |
Screen: 10 U/ml
IgG: 10 GPL U/ml
IgM: 7 MPL U/ml
IgA: 10 APL U/ml |
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| Sensitivity |
IgG: 1 GPL U/ml
IgM: 0.5 MPL U/ml
IgA: 1 APL U/ml |
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| Calibration |
Harris, IRP 97/656 (IgG) |
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| Substrate |
TMB / 450 nm |
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Instruction for Use: ORG 515-0508-01-gb.pdf
Material-Safety-Datasheet: ORG 515.pdf